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Final Program


Schedule at a Glance
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  • Saturday, Nov 11th
    1:30 PM – 3:30 PM PT
    11S103: Radiology Bootcamp
    Location: Ballroom 20D
    Moderator: Aimee Chen-Wiener, MSN, APRN – Arthritis, Autoimmune &Allergy
    Immunobiology
     CME: 2 hours
  • Saturday, Nov 11th
    1:30 PM – 2:00 PM PT
    Case-Based Assessment of Productive Arthropathies
    Location: Ballroom 20D
    Speaker: Kathleen Brindle, MD – The George Washington University Medical Faculty Associates
    Immunobiology
  • Saturday, Nov 11th
    2:00 PM – 2:10 PM PT
    Q&A
    Location: Ballroom 20D
    Immunobiology
  • Saturday, Nov 11th
    2:10 PM – 2:40 PM PT
    Case-Based Assessment of Inflammatory Arthropathies
    Location: Ballroom 20D
    Speaker: Shahriar Haji-Momenian, MD – George Washington University Medical Faculty Associates
    Immunobiology
  • Saturday, Nov 11th
    2:40 PM – 2:50 PM PT
    Q&A
    Location: Ballroom 20D
    Immunobiology
  • Saturday, Nov 11th
    2:50 PM – 3:20 PM PT
    Chest Imaging in Rheumatic Diseases
    Location: Ballroom 20D
    Speaker: John Lichtenberger, MD – The George Washington University Medical Faculty Associates
    Immunobiology
  • Saturday, Nov 11th
    3:20 PM – 3:30 PM PT
    Q&A
    Location: Ballroom 20D
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    (0001–0008) B Cell Biology & Targets in Autoimmune & Inflammatory Disease Poster
    Location: Poster Hall
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    (0009–0012) Cytokines & Cell Trafficking Poster
    Location: Poster Hall
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    (0040–0064) Innate Immunity Poster
    Location: Poster Hall
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    (0066–0095) T Cell Biology & Targets in Autoimmune & Inflammatory Disease Poster
    Location: Poster Hall
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0001: Loss of the Complement Regulator CD55 Alters Marginal Zone B Cell Homeostasis
    Location: Poster Hall
    Abstract Poster Presenter: Iris Lee, MD, RhMSUS, MSc – Washington University in St Louis
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0002: Population Pharmacokinetic and Pharmacodynamic Analyses of Obexelimab in Healthy Volunteers and in Patients with Rheumatoid Arthritis or IgG4-Related Diseases
    Location: Poster Hall
    Abstract Poster Presenter: Xiaodong Wang, PhD – Zenas BioPharma
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0004: CD22 X CD79b Bispecific Ab Potently Inhibits B Cell Activation and Plasmablast Accumulation
    Location: Poster Hall
    Abstract Poster Presenter: Edith Janssen, PhD – Janssen R&D
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0007: Targeting NF-κB Signalling in B Cells from ANCA-associated Vasculitis Impairs B Cell Biology as a Potential Novel Target
    Location: Poster Hall
    Abstract Poster Presenter: Sander Tas, MD, PhD – Amsterdam UMC, locatie AMC
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0010: A Potential Mechanism for Major Adverse Cardiac Events Associated with JAK Inhibitors: JAK Inhibitor Withdrawal Causes Urokinase Release by Primed STAT Signaling
    Location: Poster Hall
    Abstract Poster Presenter: Sara McCoy, MD, PhD, RhMSUS – University of Wisconsin
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0011: Clock Gene Bmal1 Promotes Transcriptional Activity of NF-κB to Regulate Production of Inflammatory Mediators in RA-FLS
    Location: Poster Hall
    Abstract Poster Presenter: Hikari Tsukamoto, MSc (she/her/hers) – Kobe University Graduate School of Health Sciences
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0012: Immune-cell Derived Cytokines Synergistically Interact to Drive Synovial Fibroblast Invasive Function and Metabolic Capacity
    Location: Poster Hall
    Abstract Poster Presenter: Órla Tynan, BSc (she/her/hers) – Molecular Rheumatology Department, Trinity College Dublin
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0040: Non-canonical NF-κB Signalling Is Required for Extrathymic AIRE Expression and Immunoregulatory Molecules in Cells of the Dendritic Lineage
    Location: Poster Hall
    Abstract Poster Presenter: Sander Tas, MD, PhD – Amsterdam UMC, locatie AMC
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0041: Interactions Between Synovial Fibroblasts and Macrophages: Implications for Tissue Remodeling in Chronic Inflammatory Diseases and Macrophage Differentiation in Response to the Immune Microenvironment
    Location: Poster Hall
    Abstract Poster Presenter: Jia Li, DO, DMSc – Department of Internal Medicine V, Div. of Rheumatology, University Hospital Heidelberg
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0042: Effect of the Inflammatory Microenvironment Induced by Monocytes on Fibroblasts and Modulatory Action of Human Dental Pulp Stem Cells
    Location: Poster Hall
    Abstract Poster Presenter: Elisa Pignatti, PhD – University of Modena and Reggio Emilia, Italy
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0043: Assessing the Ability of Human Dental Pulp Stem Cells to Modulate the Macrophages Phenotype
    Location: Poster Hall
    Abstract Poster Presenter: Elisa Pignatti, PhD – University of Modena and Reggio Emilia, Italy
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0044: Aberrant Mevalonate Metabolite Farnesyl Pyrophosphate-Induced Neutrophil Hyperactivation in Behçet's Disease Pathogenesis
    Location: Poster Hall
    Abstract Poster Presenter: Menghao Zhang, BS, MB (she/her/hers) – Peking Union Medical College Hospital
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0045: Discovery and Characterization of a Selective, Orally Bioavailable PAD4 Inhibitor to Target NETs Driven Autoimmune and Inflammatory Diseases
    Location: Poster Hall
    Abstract Poster Presenter: Min Yang, PhD – Regor Therapeutics
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0046: Circulating Monocytes in RA, SSc, and SLE Have Radically Altered and Unique Transcriptional & Epigenetic Profiles
    Location: Poster Hall
    Abstract Poster Presenter: Kieran Woolcock, PhD, BSc – University of Glasgow
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0047: Identification of Specific Monocyte Epigenetic Signatures in Sarcoidosis and Tuberculosis
    Location: Poster Hall
    Abstract Poster Presenter: Arthur Mageau, MD, MSc – Université Paris Cité
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0048: Monosodium Urate Crystals Activate an Immune Tolerance Program That Restrains the Activation of Inflammatory Signaling in Macrophages During Gout Flares
    Location: Poster Hall
    Abstract Poster Presenter: Mohnish Alishala, BS – University of California, San Diego
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0049: Soluble Uric Acid Is an Endogenous Inhibitor of CD38
    Location: Poster Hall
    Abstract Poster Presenter: Ikumi Tamai, PhD – Faculty of Pharmaceutical Sciences, Kanazawa University
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0050: Anti-Citrullinated Histone Antibody CIT-013, a Dual Action Therapeutic for Neutrophil Extracellular Trap Associated Autoimmune Disease
    Location: Poster Hall
    Abstract Poster Presenter: Renato G.S. Chirivi, PhD (he/him/his) – Citryll BV
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0051: CD14+CD64+ Classical Monocytes Are the Main Producers of IL-23 at the Enthesis
    Location: Poster Hall
    Abstract Poster Presenter: Nicole McDermott, PhD, BSc – University of Leeds
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0052: Possible Involvement of TLR4 in the Pathogenesis of Primary Sjögren’s Syndrome Through Induction of the Expression of BAFF Receptor, BR3 in Peripheral Monocytes
    Location: Poster Hall
    Abstract Poster Presenter: Keiko Yoshimoto, PhD (she/her/hers) – Keio University School of Medicine
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0053: Nintedanib Downregulates the Profibrotic M2 Phenotype of Macrophages Obtained from Systemic Sclerosis Patients Affected by Interstitial Lung Disease
    Location: Poster Hall
    Abstract Poster Presenter: Maurizio Cutolo, MD – University of Genova
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0054: RA Monocytes and Monocyte-Derived Macrophages Display Heightened Inflammatory Responses, Reduced Endocytic Capacity and Distinct TET Expression Compared to PsA Monocytes
    Location: Poster Hall
    Abstract Poster Presenter: Success Amaechi, BSc (he/him/his) – Trinity College Dublin
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0055: Elevated LINE-1 Expression in SLE Keratinocytes Leads to LINE-1 Reverse Transcriptase-dependent Type I Interferon Responses
    Location: Poster Hall
    Abstract Poster Presenter: Wenyan Miao, PhD – Rome Therapeutics
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0056: The Activation of cGAS-STING Pathway in Systemic Lupus Erythematosus
    Location: Poster Hall
    Abstract Poster Presenter: Jie An, PhD – University of Washington
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0057: GM-CSF receptor/SYK/JNK/FOXO1/CD11c Signaling Enhances Cell Migration to Promote Atherosclerosis
    Location: Poster Hall
    Abstract Poster Presenter: Daisuke Tsukui, MD, PhD – Teikyo University school of medicine
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0058: Macrophage Extracellular Traps Induced by Monosodium Urate or Calcium Pyrophosphate Crystals Form Independently of NLRP3 Inflammasome Activation
    Location: Poster Hall
    Abstract Poster Presenter: Diego Kyburz, MD – University Hospital Basel
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0059: GM-CSF by Natural Killer Cells Drives Inflammatory Arthritis in HIV-Infected Humanized Mice
    Location: Poster Hall
    Abstract Poster Presenter: Can Sungur, MD, PhD (he/him/his) – Mayo Clinic
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0060: Serpin B1 Modulation of Immune Complex-Mediated Neutrophil Activation and NET-formation Requires Its Chymotrypsin-like Inhibitory Activity
    Location: Poster Hall
    Abstract Poster Presenter: Christian Lood, PhD – University of Washington
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0061: Discovery of a RIPK2 Scaffolding Inhibitor for the Treatment of Joint Autoimmune Diseases
    Location: Poster Hall
    Abstract Poster Presenter: Marta Wlodarska, PhD – Odyssey Therapeutics
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0062: Differential Metabolic Profiles, Activation and Circadian Dynamics in Rheumatoid Arthritis and Psoriatic Arthritis Circulatory Monocytes
    Location: Poster Hall
    Abstract Poster Presenter: Alyssa Gilmore, PhD, BSc (she/her/hers) – Trinity College Dublin
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0063: Investigating Macrophage Repopulation in the Synovium
    Location: Poster Hall
    Abstract Poster Presenter: Jessica Maciuch, BA – Northwestern University
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0064: Correlation of Anti-DFS70 Autoantibodies by ELISA with HEp-2 Cells DFS Pattern by IFA
    Location: Poster Hall
    Abstract Poster Presenter: Vincent Ricchiuti, PhD – LabCorp
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0066: Mitochondrial Dysfunction and Fatigue in Sjögren’s Disease
    Location: Poster Hall
    Abstract Poster Presenter: Biji Kurien, PhD – Oklahoma Medical Research Foundation
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0067: Dimethyl Fumarate Modulates T Cell Metabolism and Function in Systemic Lupus Erythematosus Patient Samples
    Location: Poster Hall
    Abstract Poster Presenter: Kavina Shah, MBBS, BSc, MRCP (she/her/hers) – University College London
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0068: Anti-TNFR2 VHH Agonistic Antibodies Promote and Stabilize Treg Immunosuppressive Activity
    Location: Poster Hall
    Abstract Poster Presenter: luigi franchi, PhD – Odyssey Therapeutics
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0069: All-trans Retinoic Acid (atRA) Enhances FoxP3 Protein Stability Under Inflammatory Conditions Through Altering the FoxP3 Protein-interactome
    Location: Poster Hall
    Abstract Poster Presenter: William Willis, PhD – Ohio State University
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0070: Activation of Joint CD8+ TRM Localize Autoantibody Mediated Arthritis
    Location: Poster Hall
    Abstract Poster Presenter: Sahar Lotfi-Emran, MD, PhD (she/her/hers) – University of Minnesota
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0071: Sex Based Differences in Morphological and Functional Niches of the Human Thymus, Identified by Non-supervised Spatial Transcriptomic Profiling, May Underlie Sex Bias in Autoimmune Disease
    Location: Poster Hall
    Abstract Poster Presenter: Olov Ekwall, MD, PhD (he/him/his) – Univ Gothenburg
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0072: Circulating T-cell Immunosenescence Is High in Patients with Immune-Mediated Inflammatory Diseases (IMIDs) and Is Associated with Interferons
    Location: Poster Hall
    Abstract Poster Presenter: Samuel Bitoun, MD, PhD – CHU Bicêtre APHP
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0073: PD-1hi Cells Are Highly Present in the Rheumatoid Joint, and Express Regulatory Capacities
    Location: Poster Hall
    Abstract Poster Presenter: Stinne Greisen, PhD – Aarhus University/Aarhus University Hospital
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0074: Distinct PD-1 Receptor Engagement Leads to Different Pharmacodynamic Effects
    Location: Poster Hall
    Abstract Poster Presenter: Ling-Yang Hao, PhD – Janssen R&D
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0075: Proteomic, Transcriptomic, and T-Cell Receptor (TCR) Profiling of Synovial Integrin-Expressing (InEx) T Cells in Axial Spondyloarthritis (axSpA)
    Location: Poster Hall
    Abstract Poster Presenter: Zoya Qaiyum, MSc – Krembil Research Institute
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0076: Characterizing GMCSF Producing T-cells in Rheumatoid Arthritis and Effect of Methotrexate on Them
    Location: Poster Hall
    Abstract Poster Presenter: AASTHA KHULLAR, MSc – Postgraduate Institute of Medical Education and Research
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0077: Circulating CD4+CXCR5-PD-1hiICOS+ Cells Are Elevated in Patients with Newly Diagnosed Giant Cell Arteritis and Associate with the Clinical Outcome
    Location: Poster Hall
    Abstract Poster Presenter: Eugenio De Miguel, MD, PhD – Hospital Universitario La Paz
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0078: Circulating CD4+CXCR5+PD-1hi Follicular Helper T Cells Are Elevated in Patients with Rheumatoid Arthritis and Predict Treatment Response to Abatacept or TNF Blockers
    Location: Poster Hall
    Abstract Poster Presenter: Alejandro Balsa, MD – Hospital Universitario La Paz
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0079: CD4 T Cell Repertoire Features in RA Patients with High-risk HLA-DRB1 Alleles
    Location: Poster Hall
    Abstract Poster Presenter: Amit Lakhanpal, MD, PhD – Hospital for Special Surgery
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0080: Pharmacological Inhibition of PRMT5 Demonstrates Broad Efficacy in Multiple Preclinical Models of Autoimmunity and Inflammation by Suppressing Th1, Th17 and TNF-Mediated Inflammatory Responses
    Location: Poster Hall
    Abstract Poster Presenter: Neha Bhagwat, PhD (she/her/hers) – Prelude Therapeutics Inc.
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0081: RA Disease Activity Influence the Frequency and Phenotype of Citrulline Reactive CD4 T Cells in DRB1*04:04 ACPA+ RA Patients
    Location: Poster Hall
    Abstract Poster Presenter: Cliff Rims, BS, MHS – Benaroya Research Institute
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0082: A VAV1-Directed Molecular Glue Degrader, MRT-6160, Reduces Joint Inflammation in a Collagen-Induced Arthritis Autoimmune Disease Model
    Location: Poster Hall
    Abstract Poster Presenter: Marisa Peluso, MS – Monte Rosa Therapeutics
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0083: Expression of mRNA Vaccine Antigen in Hematopoietic Cells Is Necessary for Induction of Optimal Vaccine-Specific CD4+ T Cell Responses
    Location: Poster Hall
    Abstract Poster Presenter: Julia Rood, MD, PhD – Children's Hospital of Philadelphia
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0084: Excess IL-18 Protects from Experimental Autoimmune Encephalomyelitis Mainly via Preferential Augmentation of Suppressor/Regulatory over Autoreactive T-cell Function
    Location: Poster Hall
    Abstract Poster Presenter: Jeremy Morrissette, BS (he/him/his) – University of Pennsylvania, Perelman School of Medicine
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0085: Fibroblasts Promote Upregulation of Cannabinoid Type 2 Receptor on Inflammatory Cells in Dermatomyositis
    Location: Poster Hall
    Abstract Poster Presenter: Rohan Dhiman, BS (he/him/his) – University of Illinois Urbana Champaign
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0086: Optimizing PD-1 Agonist Signaling with Membrane Proximal Binding of Rosnilimab, a Clinical Stage PD-1 Agonist IgG1 Antibody
    Location: Poster Hall
    Abstract Poster Presenter: Stephen Parmley, PhD – AnaptysBio inc
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0087: Immune Checkpoint Inhibitor Therapy Expands an Activated, anti-PD-1 Drug-bound CD8 T Cell Population That Is Clonally Linked in Blood and Synovial Fluid of ICI-arthritis Patients
    Location: Poster Hall
    Abstract Poster Presenter: Kathryne Marks, PhD – Brigham and Women's Hospital
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0088: SLAMF4 Orchestrates the Pathological Cytotoxic Response of CD4+ T Cells in Rheumatoid Arthritis
    Location: Poster Hall
    Abstract Poster Presenter: jerome Biton, PhD – Université Sorbonne Paris Nord, Inserm UMR1125
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0089: Pre-Clinical Characterization of MTX-101, a Novel Bispecific CD8 Treg Modulator with the Potential to Restore CD8 Treg Functions in Patients with Rheumatological Autoimmune Diseases
    Location: Poster Hall
    Abstract Poster Presenter: Daniel Patton, PhD – Mozart Therapeutics
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0090: Reduced Frequency of RORγt+ Regulatory T Cells Is Associated with Secukinumab Response in Axial Spondyloarthritis
    Location: Poster Hall
    Abstract Poster Presenter: Addison Pacheco, BSc (he/him/his) – University Health Network
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0091: Impaired X-Chromosome Inactivation Maintenance in T Cells Is Associated with Features of Reduced Disease Severity in a Toll-Like Receptor 7-Driven Model of Systemic Autoimmunity
    Location: Poster Hall
    Abstract Poster Presenter: Nikhil Jiwrajka, MD – Hospital of the University of Pennsylvania
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0092: Multi-omics Immune Profiling of Cytotoxic T Cells from Ankylosing Spondylitis Patients Identified a Subset of Clonally Exapnded CTLs That Evade Immune Exhaustion
    Location: Poster Hall
    Abstract Poster Presenter: Zoya Qaiyum, MSc – Krembil Research Institute
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0093: Single Cell RNA-seq and Mass Cytometry Reveal a Cytotoxic CD8 Effector T Cell Population Associated with Interstitial Lung Disease in Systemic Sclerosis Patients
    Location: Poster Hall
    Abstract Poster Presenter: Ye Cao, PhD – Brigham and Women's Hospital
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0094: Granzyme K Elicits a New Pathway for Complement Activation in RA Synovium
    Location: Poster Hall
    Abstract Poster Presenter: Anna Helena Jonsson, MD, PhD – Brigham and Women's Hospital
    Immunobiology
  • Sunday, Nov 12th
    9:00 AM – 11:00 AM PT
    0095: Kynurenine Is a Proinflammatory Metabolite That Activates a Positive Feedback Loop of Rab4A-dependent CD98 Expression and mTORC1 and mTORC2 Activation in SLE
    Location: Poster Hall
    Abstract Poster Presenter: Thomas Winans, PhD – SUNY Upstate Medical University
    Immunobiology
  • Sunday, Nov 12th
    2:00 PM – 3:30 PM PT
    12S140: Abstracts: B Cell Biology & Targets in Autoimmune & Inflammatory Disease (0727–0732)
    Location: Room 30D-E
    Abstract Moderator: Keith Elkon, MD – University of Washington
    Abstract Moderator: David Isenberg, MD, FRCP – University College London
    Immunobiology
  • Sunday, Nov 12th
    2:00 PM – 2:10 PM PT
    0727: A Novel Active Pemphigus Vulgaris Mouse Model Induced by Immunization with TLR Ligand Adjuvanted Recombinant Desmoglein 3 Protein Vaccine
    Location: Room 30D-E
    Presenting Author: Changxing Gao, PhD – Peking Union Medical College
    Immunobiology
  • Sunday, Nov 12th
    2:15 PM – 2:25 PM PT
    0728: Systemic Lupus Erythematosus B Lymphocyte Responsiveness to Type I and Type III Interferon Is Determined by Donor IFN Status and B Cell Phenotype
    Location: Room 30D-E
    Presenting Author: Jennifer Barnas, MD, PhD, BS – University of Rochester
    Immunobiology
  • Sunday, Nov 12th
    2:30 PM – 2:40 PM PT
    0729: ROCK1 Orchestrates B-cell Differentiation Under Stress
    Location: Room 30D-E
    Presenting Author: Alessandra Pernis, MD – Hospital for Special Surgery
    Immunobiology
  • Sunday, Nov 12th
    2:45 PM – 2:55 PM PT
    0730: NF-κB Signaling Is Critically Important for Functional Responses of ACPA-producing B Cell Clones from Patients with Rheumatoid Arthritis
    Location: Room 30D-E
    Presenting Author: Sander Tas, MD, PhD – Amsterdam UMC, locatie AMC
    Immunobiology
  • Sunday, Nov 12th
    3:00 PM – 3:10 PM PT
    0731: ZEB2 Acts as a Crucial Transcriptional Regulator Governing Age-Associated B Cell Formation and Pathogenicity in Systemic Lupus Erythematosus
    Location: Room 30D-E
    Presenting Author: Nan Shen, MD, PhD – Shanghai Jiang Tong University School of Medicine
    Immunobiology
  • Sunday, Nov 12th
    3:15 PM – 3:25 PM PT
    0732: Should Complete B-cell Depletion Be Maintained in Patients Treated Long-term with Rituximab for Rheumatoid Arthritis?
    Location: Room 30D-E
    Presenting Author: Roba Ghossan, MD – COCHIN HOSPITAL
    Immunobiology
  • Sunday, Nov 12th
    4:00 PM – 5:00 PM PT
    12S156: Just Roll with It: The Basics of Neutrophil Biology
    Location: Room 31A-C
    Moderator: Tomas Mustelin, MD, PhD – University of Washington
    Immunobiology
     CME: 1 hours
  • Sunday, Nov 12th
    4:00 PM – 4:25 PM PT
    Neutrophil Trafficking and Function
    Location: Room 31A-C
    Speaker: Paul Kubes, PhD – University of Calgary
    Immunobiology
  • Sunday, Nov 12th
    4:25 PM – 4:50 PM PT
    Neutrophils as Regulators of Thrombosis
    Location: Room 31A-C
    Speaker: Tobias Petzold, MD, PhD – University of Munich
    Immunobiology
  • Sunday, Nov 12th
    4:50 PM – 5:00 PM PT
    Q&A
    Location: Room 31A-C
    Immunobiology
  • Sunday, Nov 12th
    4:00 PM – 5:30 PM PT
    12S169: Abstracts: T Cell Biology & Targets in Autoimmune & Inflammatory Disease (0799–0804)
    Location: Room 30D-E
    Abstract Moderator: Milena Vukelic, MD – Albert Einstein College of Medicine
    Abstract Moderator: Jason Weinstein, PhD – Rutgers New Jersey Medical School
    Immunobiology
  • Sunday, Nov 12th
    4:00 PM – 4:10 PM PT
    0799: Human Chimeric Antigen Receptor (CAR)-Tregs Targeting OX40L for Treatment of Systemic Lupus Erythematosus
    Location: Room 30D-E
    Presenting Author: Holly Wobma, MD, PhD (she/her/hers) – Boston Children's Hospital
    Immunobiology
  • Sunday, Nov 12th
    4:15 PM – 4:25 PM PT
    0800: CD4+ CD96+ T Cells Are Pathogenic Effector Cells in Giant Cell Arteritis
    Location: Room 30D-E
    Presenting Author: Shozo Ohtsuki, PhD, MS – Mayo Clinic College of Medicine and Science
    Immunobiology
  • Sunday, Nov 12th
    4:30 PM – 4:40 PM PT
    0801: LncRNA PIGL-217 Regulates Th17 Differentiation by Targeting miR-5008-5p and Suppressing FoxO1 in Behçet's Disease
    Location: Room 30D-E
    Presenting Author: Zhimian Wang, MB (she/her/hers) – Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
    Immunobiology
  • Sunday, Nov 12th
    4:45 PM – 4:55 PM PT
    0802: Targeting Fibroblasts in Inflammatory Disease Using Engineered T Cells
    Location: Room 30D-E
    Presenting Author: Samuel Kemble, PhD, BSc – University Birmingham
    Immunobiology
  • Sunday, Nov 12th
    5:00 PM – 5:10 PM PT
    0803: IL10 Inhibits Toll-like Receptor-9-induced T Cell Receptor-mediated T Cell Activation in Macrophage Activation Syndrome
    Location: Room 30D-E
    Presenting Author: Matthew Eremita, MD – Northwell Health / Cohen Children's Medical Center
    Immunobiology
  • Sunday, Nov 12th
    5:15 PM – 5:25 PM PT
    0804: Mutated NOD2 Controls IL-2 Production in Blau Syndrome Patients and Mice
    Location: Room 30D-E
    Presenting Author: Leah Huey, BS – Oregon Health & Science University
    Immunobiology
  • Monday, Nov 13th
    8:00 AM – 9:00 AM PT
    13M110: Getting Past Central Nervous System Vasculitis: Mimics Galore
    Location: Room 8
    Moderator: Ekemini Ogbu, MD, MSc – Cincinnati Children's Hospital Medical Center
    Immunobiology
     CME: 1 hours
  • Monday, Nov 13th
    8:00 AM – 9:00 AM PT
    13M111: The Art of Dying Well: Novel Insights into Cell Death
    Location: Room 30D-E
    Moderator: Keith Elkon, MD – University of Washington
    Immunobiology
     CME: 1 hours
  • Monday, Nov 13th
    8:00 AM – 8:20 AM PT
    Necroptosis
    Location: Room 30D-E
    Speaker: Andrew Oberst, PhD – University of Washington
    Immunobiology
  • Monday, Nov 13th
    8:00 AM – 8:25 AM PT
    Demyelinating Disorders in Children: Overlapping Features with Rheumatic Disorders
    Location: Room 8
    Speaker: Jennifer Graves, MD, PhD – UC San Diego Health
    Immunobiology
  • Monday, Nov 13th
    8:20 AM – 8:30 AM PT
    Q&A
    Location: Room 30D-E
    Immunobiology
  • Monday, Nov 13th
    8:25 AM – 8:50 AM PT
    Mitochondrial Disorders and Central Nervous System Dysfunction: A Pediatric Rheumatologist's Practical Overview for the Pediatric Rheumatologist
    Location: Room 8
    Speaker: Jennifer Yang, MD – University California San Diego / Rady Children's Hospital San Diego
    Immunobiology
  • Monday, Nov 13th
    8:30 AM – 8:50 AM PT
    Cell Death in the Kidney
    Location: Room 30D-E
    Speaker: Michael Balzer – Charité Universitätsmedizin Berlin
    Immunobiology
  • Monday, Nov 13th
    8:50 AM – 9:00 AM PT
    Q&A
    Location: Room 30D-E
    Immunobiology
  • Monday, Nov 13th
    8:50 AM – 9:00 AM PT
    Q&A
    Location: Room 8
    Immunobiology
  • Monday, Nov 13th
    11:15 AM – 11:25 AM PT
    1580: CXCL13+ T Cell Differentiation in Systemic Lupus Erythematosus Is Controlled by Opposing Effects of Aryl Hydrocarbon Receptor and Type I Interferon
    Location: Exhibit Hall A-B
    Plenary Presenter: Calvin Law, PhD (he/him/his) – Northwestern University Feinberg School of Medicine
    Immunobiology
  • Monday, Nov 13th
    12:00 PM – 1:00 PM PT
    13M128: Immunology Bootcamp I: Basic Principles
    Location: Room 6E/6D
    Moderator: Gregg Silverman, MD – NYU Grossman School of Medicine
    Immunobiology
     CME: 1 hours
  • Monday, Nov 13th
    12:00 PM – 1:00 PM PT
    13M129: Immunometabolism in Autoimmune Disease
    Location: Room 30D-E
    Moderator: Monica Guma, MD, PhD – UCSD
    Moderator: Hu Zeng, PhD – Mayo Clinic
    Immunobiology
     CME: 1 hours
  • Monday, Nov 13th
    12:00 PM – 12:15 PM PT
    Metabolic Mechanisms That Control Inflammation and Immune-Related Disorders
    Location: Room 30D-E
    Speaker: Jeffrey Rathmell, PhD – Vanderbilt University Medical Center
    Immunobiology
  • Monday, Nov 13th
    12:00 PM – 12:45 PM PT
    Immunology Bootcamp I: Basic Principles
    Location: Room 6E/6D
    Speaker: Troy Torgerson – Allen Institute for Immunology
    Immunobiology
  • Monday, Nov 13th
    12:15 PM – 12:30 PM PT
    Immunometabolism and Trained Immunity in Autoimmune Disease
    Location: Room 30D-E
    Speaker: Caroline Jefferies, PhD – Cedars-Sinai Medical Center
    Immunobiology
  • Monday, Nov 13th
    12:30 PM – 12:45 PM PT
    Metabolism of Autoantibody Production in Lupus
    Location: Room 30D-E
    Speaker: Laurence Morel, PhD – University of Texas health San Antonio
    Immunobiology
  • Monday, Nov 13th
    12:45 PM – 1:00 PM PT
    Q&A
    Location: Room 30D-E
    Immunobiology
  • Monday, Nov 13th
    12:45 PM – 1:00 PM PT
    Q&A
    Location: Room 6E/6D
    Immunobiology
  • Monday, Nov 13th
    2:00 PM – 3:00 PM PT
    13M137: Cutting Through the Brain Fog: Cognitive Dysfunction in Lupus
    Location: Room 31A-C
    Moderator: Sarfaraz Hasni, MD, MSc – National Institutes of Health
    Immunobiology
     CME: 1 hours
  • Monday, Nov 13th
    2:00 PM – 2:15 PM PT
    Functional MRI in CNS Lupus
    Location: Room 31A-C
    Speaker: Ian N. Bruce, MD – University of Manchester
    Immunobiology
  • Monday, Nov 13th
    2:15 PM – 2:30 PM PT
    Metabolism in Central Nervous System Lupus
    Location: Room 31A-C
    Immunobiology
  • Monday, Nov 13th
    2:30 PM – 2:45 PM PT
    Microglia in Central Nervous System Lupus
    Location: Room 31A-C
    Speaker: Carla Cuda, PhD – Northwestern University
    Immunobiology
  • Monday, Nov 13th
    2:45 PM – 3:00 PM PT
    Q&A
    Location: Room 31A-C
    Immunobiology
  • Monday, Nov 13th
    2:00 PM – 3:30 PM PT
    13M144: Abstracts: Innate Immunity (1585–1590)
    Location: Room 32A-B
    Abstract Moderator: Judith Smith, MD, PhD – University of Wisconsin
    Abstract Moderator: Christian Lood, PhD – University of Washington
    Immunobiology
  • Monday, Nov 13th
    2:00 PM – 2:10 PM PT
    1585: Defining Neutrophil-Mediated Renal Damage Triggered by Ultraviolet (UV) Skin Exposure
    Location: Room 32A-B
    Presenting Author: Angelique Cortez, BS (she/her/hers) – Dartmouth College
    Immunobiology
  • Monday, Nov 13th
    2:15 PM – 2:25 PM PT
    1586: Keratinocyte VISTA Suppresses Skin IFN-I Production by Regulating DNA Damage Repair and Cytosolic DNA Sensing
    Location: Room 32A-B
    Presenting Author: Zachary Peters, BA – Dartmouth
    Immunobiology
  • Monday, Nov 13th
    2:30 PM – 2:40 PM PT
    1587: Mitochondrial Z-DNA and ZBP1 Drive Autoimmune Photosensitivity
    Location: Room 32A-B
    Presenting Author: Benjamin Klein, MD (he/him/his) – University of Michigan
    Immunobiology
  • Monday, Nov 13th
    2:45 PM – 2:55 PM PT
    1588: Monocyte-derived Macrophages Accumulate in the Lungs in anti-MDA5+ Dermatomyositis with RP-ILD: Proinflammatory and Profibrotic Phenotype Revealed by Single-cell RNA Sequencing
    Location: Room 32A-B
    Presenting Author: Jia Shi, MD – Peking Union Medical College
    Immunobiology
  • Monday, Nov 13th
    3:00 PM – 3:10 PM PT
    1589: Epigenetic Regulation of DNMT3A by TFEB and DOT1L Through AMPK Signalling Orchestrates the Lysosomal Response of Macrophages During Gout and Clonal Hematopoiesis
    Location: Room 32A-B
    Presenting Author: Isidoro Cobo, PhD – University of California San Diego
    Immunobiology
  • Monday, Nov 13th
    3:15 PM – 3:25 PM PT
    1590: Autoimmune Pathway Blockade by a Potent Orally Bioavailable STING Antagonist
    Location: Room 32A-B
    Presenting Author: Min Yang, PhD – Regor Therapeutics
    Immunobiology
  • Monday, Nov 13th
    4:00 PM – 5:30 PM PT
    13M170: The Forgotten (Non-nucleated) Cells of Autoimmune Disease: RBCs, Platelets and the Bone Marrow Niche
    Location: Room 30D-E
    Moderator: Betsy Barnes, PhD – Northwell Health
    Moderator: Christian Lood, PhD – University of Washington
    Immunobiology
     CME: 1.5 hours
  • Monday, Nov 13th
    4:00 PM – 4:20 PM PT
    Erythromyeloblastic Islands
    Location: Room 30D-E
    Speaker: Lionel Blanc, PhD – Feinstein Institutes for Medical Research
    Immunobiology
  • Monday, Nov 13th
    4:20 PM – 4:30 PM PT
    Q&A
    Location: Room 30D-E
    Immunobiology
  • Monday, Nov 13th
    4:30 PM – 4:50 PM PT
    HSCs and Autoimmunity
    Location: Room 30D-E
    Speaker: Katherine King, MD, PhD – Baylor College of Medicine
    Immunobiology
  • Monday, Nov 13th
    4:50 PM – 5:00 PM PT
    Q&A
    Location: Room 30D-E
    Immunobiology
  • Monday, Nov 13th
    5:00 PM – 5:20 PM PT
    Platelets/Iron Stores and Inflammation
    Location: Room 30D-E
    Speaker: Craig Morrell, PhD, DVM – University of Rochester
    Immunobiology
  • Monday, Nov 13th
    5:20 PM – 5:30 PM PT
    Q&A
    Location: Room 30D-E
    Immunobiology
  • Tuesday, Nov 14th
    7:30 AM – 8:15 AM PT
    14T101: Beyond Nature v. Nurture: Evidence of Early Life Influences on Immunity
    Location: Room 7A-B
    Moderator: Erica Schmitt, MD, PhD – Washington University in St. Louis
    Immunobiology
     CME: 0.75 hours
  • Tuesday, Nov 14th
    7:30 AM – 7:45 AM PT
    Long-Term Impacts of Early Life Infection and Inflammation on Immunity
    Location: Room 7A-B
    Speaker: Jennifer Bermick, MD – University of Iowa
    Immunobiology
  • Tuesday, Nov 14th
    7:45 AM – 8:00 AM PT
    Long-Term Effects on Immunity from T Regulatory Cells Established Early in Life
    Location: Room 7A-B
    Speaker: Rodney Newberry, MD – Washington University in St. Louis
    Immunobiology
  • Tuesday, Nov 14th
    8:00 AM – 8:15 AM PT
    Q&A
    Location: Room 7A-B
    Immunobiology
  • Tuesday, Nov 14th
    7:30 AM – 8:30 AM PT
    14T104: CARs as "Drivers" of Precision Cellular Immunotherapies for Autoimmune Diseases
    Location: Exhibit Hall A-B
    Moderator: Maximilian Konig, MD – The Johns Hopkins University School of Medicine
    Immunobiology
     CME: 1 hours
  • Tuesday, Nov 14th
    7:30 AM – 7:45 AM PT
    Methods for Cutting-Edge Engineering of the Immune System
    Location: Exhibit Hall A-B
    Speaker: Michel Sadelain, MD, PhD – Memorial Sloan Kettering Cancer Center
    Immunobiology
  • Tuesday, Nov 14th
    7:45 AM – 8:00 AM PT
    Immunological Consequences of CAR T Cell Treatment of Refractory Systemic Lupus Erythematosus
    Location: Exhibit Hall A-B
    Speaker: Georg Schett, MD – Friedrich-Alexander-Universität Erlangen-Nürnberg
    Immunobiology
  • Tuesday, Nov 14th
    8:00 AM – 8:15 AM PT
    Antigen-Specific Depletion of CD4+ T Cells in Experimental Autoimmune Encephalomyelitis
    Location: Exhibit Hall A-B
    Speaker: Chyi-Song Hsieh, MD, PhD – Washington University
    Immunobiology
  • Tuesday, Nov 14th
    8:15 AM – 8:30 AM PT
    Q&A
    Location: Exhibit Hall A-B
    Immunobiology
  • Tuesday, Nov 14th
    12:00 PM – 1:00 PM PT
    14T133: Immunology Bootcamp II: Principles in Practice
    Location: Room 23A-C
    Moderator: Janet Bahr, NP – Gundersen Health
    Immunobiology
     CME: 1 hours
  • Tuesday, Nov 14th
    12:00 PM – 1:00 PM PT
    14T134: Improving the Immune Landscape Using Biomaterials
    Location: Room 29A-D
    Moderator: Antonio La Cava, MD, PhD – University of California Los Angeles
    Immunobiology
     CME: 1 hours
  • Tuesday, Nov 14th
    12:00 PM – 1:00 PM PT
    14T138: The Eyes Have It: Ocular Mucosal Immunity
    Location: Room 25A-C
    Moderator: Lisa Carnago, FNP-C – Duke Health
    Moderator: Michael Paley, MD, PhD – Washington University in St. Louis
    Immunobiology
     CME: 1 hours
  • Tuesday, Nov 14th
    12:00 PM – 12:15 PM PT
    Microbiota as Drivers and as Therapeutic Targets in Ocular and Tissue-Specific Autoimmunity
    Location: Room 25A-C
    Speaker: Anthony St. Leger, PhD – University of Pittsburgh
    Immunobiology
  • Tuesday, Nov 14th
    12:00 PM – 12:20 PM PT
    Harnessing Biomaterials for Immunomodulatory-Driven Tissue Engineering
    Location: Room 29A-D
    Immunobiology
  • Tuesday, Nov 14th
    12:00 PM – 12:45 PM PT
    Immunology Bootcamp II: Principles in Practice
    Location: Room 23A-C
    Speaker: Troy Torgerson – Allen Institute for Immunology
    Immunobiology
  • Tuesday, Nov 14th
    12:15 PM – 12:30 PM PT
    Mucosal Immunity of the Ocular Surface: The Role of Barrier Function and Innate Responses in Homeostasis and Disease
    Location: Room 25A-C
    Speaker: Cintia S. De Paiva, MD, PhD – Baylor College of Medicine
    Immunobiology
  • Tuesday, Nov 14th
    12:20 PM – 12:30 PM PT
    Q&A
    Location: Room 29A-D
    Immunobiology
  • Tuesday, Nov 14th
    12:30 PM – 12:45 PM PT
    Understanding the Interactions Between Ocular Surface Microbiome and Innate Immune System
    Location: Room 25A-C
    Speaker: Mary Mattapallil, PhD – NEI/NIH
    Immunobiology
  • Tuesday, Nov 14th
    12:30 PM – 12:50 PM PT
    Targeted Nanotherapy for Induction of Therapeutic Immune Responses
    Location: Room 29A-D
    Speaker: tarek fahmy, PhD – Yale University
    Immunobiology
  • Tuesday, Nov 14th
    12:45 PM – 1:00 PM PT
    Q&A
    Location: Room 25A-C
    Immunobiology
  • Tuesday, Nov 14th
    12:45 PM – 1:00 PM PT
    Q&A
    Location: Room 23A-C
    Immunobiology
  • Tuesday, Nov 14th
    12:50 PM – 1:00 PM PT
    Q&A
    Location: Room 29A-D
    Immunobiology
  • Tuesday, Nov 14th
    2:00 PM – 3:00 PM PT
    14T148: Tipping the Scale: Interactions Between Obesity and Inflammation
    Location: Room 31A-C
    Moderator: Jon Giles, MD, MPH – Columbia University
    Immunobiology
     CME: 1 hours
  • Tuesday, Nov 14th
    2:00 PM – 2:20 PM PT
    Immune Impacts of Obesity
    Location: Room 31A-C
    Speaker: Sagar Bapat, MD, PhD – University of California San Francisco
    Immunobiology
  • Tuesday, Nov 14th
    2:20 PM – 2:30 PM PT
    Q&A
    Location: Room 31A-C
    Immunobiology
  • Tuesday, Nov 14th
    2:30 PM – 2:50 PM PT
    TSLP-Driven Adipose Loss
    Location: Room 31A-C
    Speaker: Taku Kambayashi, MD, PhD – University of Pennsylvania
    Immunobiology
  • Tuesday, Nov 14th
    2:50 PM – 3:00 PM PT
    Q&A
    Location: Room 31A-C
    Immunobiology
  • Tuesday, Nov 14th
    4:00 PM – 5:00 PM PT
    14T168: Toxic Immune Environment: The Role of T Cells in Tissue Wellbeing
    Location: Room 30D-E
    Moderator: Anna Helena Jonsson, MD, PhD – Brigham and Women's Hospital
    Immunobiology
     CME: 1 hours
  • Tuesday, Nov 14th
    4:00 PM – 4:15 PM PT
    Cytotoxic CD4+ T Lymphocytes May Induce Endothelial Cell Apoptosis in Systemic Sclerosis
    Location: Room 30D-E
    Speaker: Cory Perugino, DO – Massachusetts General Hospital
    Immunobiology
  • Tuesday, Nov 14th
    4:15 PM – 4:30 PM PT
    Cytotoxic CD8+ T Cells Target Citrullinated Antigens in Rheumatoid Arthritis
    Location: Room 30D-E
    Speaker: William H. Robinson, MD, PhD – Stanford University
    Immunobiology
  • Tuesday, Nov 14th
    4:30 PM – 4:45 PM PT
    KIR+CD8+T Cells Suppress Pathogenic T Cells and Are Active in Autoimmune Diseases and COVID-19
    Location: Room 30D-E
    Speaker: Jing Li, PhD – University of Pittsburgh
    Immunobiology
  • Tuesday, Nov 14th
    4:45 PM – 5:00 PM PT
    Q&A
    Location: Room 30D-E
    Immunobiology
  • Tuesday, Nov 14th
    4:00 PM – 5:30 PM PT
    14T170: Abstracts: Cytokines & Cell Trafficking (2503–2508)
    Location: Room 29A-D
    Abstract Moderator: Monica Guma, MD, PhD – UCSD
    Immunobiology
  • Tuesday, Nov 14th
    4:00 PM – 5:30 PM PT
    14T180: More Than Complementary Pathways: Where Coagulation and Complement Converge
    Location: Room 31A-C
    Moderator: Jason Knight, MD, PhD – University of Michigan
    Immunobiology
     CME: 1.5 hours
  • Tuesday, Nov 14th
    4:00 PM – 5:30 PM PT
    14T181: Pulmonary Arterial Hypertension for the Rheumatologist and Immunologist
    Location: Room 7A-B
    Moderator: DeAnna Baker Frost, MD, PhD – Medical University of South Carolina
    Moderator: Carol Feghali-Bostwick, PhD – Medical University of South Carolina
    Immunobiology
     CME: 1.5 hours
  • Tuesday, Nov 14th
    4:00 PM – 4:10 PM PT
    2503: Cytokines Regulate the Fibrotic Response of Growth Factors in Joint Fibroblast-like Synoviocytes
    Location: Room 29A-D
    Presenting Author: Sofie Falkenløve Madsen, MSc (she/her/hers) – University of Copenhagen
    Immunobiology
  • Tuesday, Nov 14th
    4:00 PM – 4:20 PM PT
    Intersection of the Complement and Coagulation Pathways
    Location: Room 31A-C
    Speaker: Keith McCrae, MD – Cleveland Clinic
    Immunobiology
  • Tuesday, Nov 14th
    4:00 PM – 4:20 PM PT
    Pulmonary Arterial Hypertension Overview: Diagnostic and Treatment Considerations for Rheumatologists
    Location: Room 7A-B
    Speaker: Lorinda Chung, MD, MS (she/her/hers) – Stanford University
    Immunobiology
  • Tuesday, Nov 14th
    4:15 PM – 4:25 PM PT
    2504: The Effect of Inflammatory Conditions on the Regulation of Canonical and Non-canonical NF-kB Pathways via Bcl11b
    Location: Room 29A-D
    Presenting Author: Sara Parsa, PhD – Erasmus Medical Center
    Immunobiology
  • Tuesday, Nov 14th
    4:20 PM – 4:30 PM PT
    Q&A
    Location: Room 31A-C
    Immunobiology
  • Tuesday, Nov 14th
    4:30 PM – 4:40 PM PT
    2505: Discovery of First-in-Class IRAK4 Scaffolding Inhibitors for the Treatment of Inflammatory Disorders
    Location: Room 29A-D
    Presenting Author: Kate Byth, PhD, MA – Odyssey Therapeutics
    Immunobiology
  • Tuesday, Nov 14th
    4:30 PM – 4:50 PM PT
    Crosstalk Between the Complement and Coagulation Systems in Antiphospholipid Syndrome
    Location: Room 31A-C
    Speaker: Francesco Tedesco, MD – Istituto Auxologico Italiano, IRCCS, Milan, Italy
    Immunobiology
  • Tuesday, Nov 14th
    4:30 PM – 4:50 PM PT
    State-of-the-Art Pulmonary Arterial Hypertension: From Animal Models to the Rheumatology Clinic
    Location: Room 7A-B
    Speaker: Benjamin Korman, MD – University of Rochester
    Immunobiology
  • Tuesday, Nov 14th
    4:45 PM – 4:55 PM PT
    2506: Role of TGF-β Activated Kinase 1 in Cytokine-Driven Juvenile Idiopathic Arthritis Synovial Fibroblasts Activation
    Location: Room 29A-D
    Presenting Author: Meena Afroze Shanta, MS – College of Pharmacy and Pharmaceutical Science, Washington State University
    Immunobiology
  • Tuesday, Nov 14th
    4:50 PM – 5:00 PM PT
    Q&A
    Location: Room 31A-C
    Immunobiology
  • Tuesday, Nov 14th
    5:00 PM – 5:10 PM PT
    2507: ZCCHC6 Modulates the Global Phosphorylation Landscape in TNF-a-induced Rheumatoid Arthritis Synovial Fibroblasts
    Location: Room 29A-D
    Presenting Author: Anil Singh, PhD – Washington State university
    Immunobiology
  • Tuesday, Nov 14th
    5:00 PM – 5:20 PM PT
    Complement, Coagulation, and the Kidney
    Location: Room 31A-C
    Speaker: Joshua Thurman, MD – University of Colorado
    Immunobiology
  • Tuesday, Nov 14th
    5:00 PM – 5:20 PM PT
    Sotatercept: Mechanism of Action and How It Differs from Previous PAH Treatment
    Location: Room 7A-B
    Speaker: Lewis Rubin, MD – UC San Diego
    Immunobiology
  • Tuesday, Nov 14th
    5:15 PM – 5:25 PM PT
    2508: Chronic IL-6 Trans-Signaling Enhances Stem Cell-Like Characteristics of Rheumatoid Arthritis Synovial Fibroblasts
    Location: Room 29A-D
    Presenting Author: Anil Singh, PhD – Washington State university
    Immunobiology
  • Tuesday, Nov 14th
    5:20 PM – 5:30 PM PT
    Q&A
    Location: Room 31A-C
    Immunobiology
  • Tuesday, Nov 14th
    5:20 PM – 5:30 PM PT
    Q&A
    Location: Room 7A-B
    Immunobiology
  • Wednesday, Nov 15th
    9:15 AM – 10:15 AM PT
    15W113: Humoral Immunity Gone Wrong: Antibody Secreting B Cells
    Location: Room 30D-E
    Moderator: Alessandra Pernis, MD – Hospital for Special Surgery
    Immunobiology
     CME: 1 hours
  • Wednesday, Nov 15th
    9:15 AM – 9:30 AM PT
    Germinal Center Checkpoint in Lupus
    Location: Room 30D-E
    Speaker: Ziaur Rahman, MD, PhD – Thomas Jefferson University
    Immunobiology
  • Wednesday, Nov 15th
    9:30 AM – 9:45 AM PT
    Clone Tracking and B Cell Subset Analysis in Autoimmunity
    Location: Room 30D-E
    Speaker: James Knox, PhD – University of Pennsylvania
    Immunobiology
  • Wednesday, Nov 15th
    9:45 AM – 10:00 AM PT
    Extrafollicular Effector B Cells Contributions to Autoantibody Production in Systemic Lupus Erythematosus
    Location: Room 30D-E
    Speaker: Betty Tsao, PhD – Medical University of South Carolina
    Immunobiology
  • Wednesday, Nov 15th
    10:00 AM – 10:15 AM PT
    Q&A
    Location: Room 30D-E
    Immunobiology
  • Wednesday, Nov 15th
    11:00 AM – 12:00 PM PT
    15W122: Genes, Gender, and Gammaglogulins in Severe COVID: Lessons Learned from the Pandemic
    Location: Room 30D-E
    Moderator: Alfred Kim, MD, PhD (he/him/his) – Washington University School of Medicine
    Moderator: Rebecca Sadun, MD, PhD – Duke University
    Immunobiology
     CME: 1 hours
  • Wednesday, Nov 15th
    11:00 AM – 11:45 AM PT
    Genes, Gender, and Gammaglogulins in Severe COVID: Lessons Learned From the Pandemic
    Location: Room 30D-E
    Speaker: Jean-Laurent Casanova (he/him/his) – IHU Imagine, AP-HP Necker
    Immunobiology
  • Wednesday, Nov 15th
    11:45 AM – 12:00 PM PT
    Q&A
    Location: Room 30D-E
    Immunobiology