Genetics, genomics and proteomics
Leah Kottyan, PhD
Cincinnati Children's Hospital
Cincinnati, OH, United States
Disclosure(s): No financial relationships with ineligible companies to disclose
Nan Shen, MD, PhD
Shanghai Jiang Tong University School of Medicine
Shanghai, Shanghai, China
Disclosure(s): No financial relationships with ineligible companies to disclose
Much discussion and investigation rightly focuses into the impact of genetic variants in coding DNA. This type of variant, resulting in changes in important immune proteins, can alter the way the immune response develops, activates and sometimes dysregulates. But many non-coding variants have been linked to rheumatic diseases as well. The functional effects of non-coding variants are more difficult to elucidate, but new immunologic, sequencing, and bioinformatic techniques have allowed for explorations into the roles of non-coding variation. This session will explore recent developments in interpretation of the impacts of findings from genome wide association studies (GWAS) and the role of non-coding RNAs in inflammatory disease
Speaker: Leah Kottyan, PhD – Cincinnati Children's Hospital
Speaker: Nan Shen, MD, PhD – Shanghai Jiang Tong University School of Medicine
