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Final Program


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Mara Becker, MD

Duke University Medical Center/Duke Clinical Research Institute
Chapel Hill, NC, United States

Dr. Becker is a Professor of Pediatrics at Duke University School of Medicine where she serves as the Vice Dean for Faculty in the School of Medicine. She is also a faculty member in the Duke Clinical Research Institute where she serves as PI for the DCRI Coordinating Center for the CARRA Registry. Dr. Becker’s research interest is to identify factors that enhance response and minimize toxicity to drugs used for the treatment of diseases in children, focusing on an individualized therapeutic strategy. Her translational research has focused on methotrexate and its effect upon the folate pathway, utilizing cellular biomarkers and genetic differences to predict drug efficacy and minimize toxicity in patients with JIA. Her work has expanded to include the investigation of novel cytokine biomarkers and metabolomics, the interrogation of the folate pathway in patients with Down syndrome, and the exploration of biologic therapeutic drug monitoring in JIA and IBD. Throughout the years, her work has been funded by the Kansas City Areas Life Sciences Institute, the PhRMA Foundation, the Rheumatology Research Foundation and the National Institutes of Health. Dr. Becker has held multiple leadership roles in national committees and organizations in her field, including serving on the FDA Arthritis Advisory Committee from 2015-2023.

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