University of Michigan
Ann Arbor, MI, United States
I have an extensive experience in molecular biology, immunology, pathology, inflammation, autoimmune skin, and fibrotic disease research.
As a DVM, PhD scientist, I have a broad experience in the field of autoimmune skin diseases. My research focuses on the pathogenic mechanisms that drive skin and systemic inflammation in systemic lupus erythematosus (SLE) patients. My research also involves in understanding the molecular mechanisms of psoriasis, dermatomyositis, tissue injury, inflammation in cutaneous lupus, scleroderma, atopic dermatitis, and other autoimmune diseases.
My current research involves in SLE and fibrotic diseases at the Department of Internal Medicine-Rheumatology and Dermatology. I am studying the role of VGLL3 as a primary orchestrator of sex bias in autoimmune diseases, chronic inflammation, and fibrosis, including: 1) activation and repression of signaling mechanisms that engage in epithelial, fibroblast proliferation, epithelial, mesenchymal transformation, and myofibroblast differentiation 2) gene transcription by secreted inflammatory cytokines and chemokines in chronic inflammation; fibrotic diseases of the skin, lung, kidney, and liver. Using a combination of murine models, molecular and cellular biology.
Also, as team scientist, we are working in several project in identification, validation of fibrosis, scleroderma, dermatitis, lupus, and psoriasis biomarkers, using single -cell RNA sequencing (sc-RNA seq), ATAG and multiome seq.
Monday, November 13, 2023
9:00 AM – 11:00 AM PT
Disclosure information not submitted.
