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Scientific Session

Sjögren’s syndrome
General Topic: Clinical Science

13M156: Challenging Complications of the Nervous System in Sjögren's Syndrome

Monday, November 13, 2023
4:00 PM – 5:00 PM PT
Location: Room 1A-B
CE: 1

In Person On Demand

    Speaker(s)

  • JB

    Julius Birnbaum, MD

    1 University of Pittsburgh Medical Center
    Wexford, PA, United States

    Disclosure(s): No financial relationships with ineligible companies to disclose

  • BG

    Brent Goodman, MD

    Mayo Clinic
    Scottsdale, AZ, United States

    Disclosure(s): No financial relationships with ineligible companies to disclose

  • AV

    Arun Varadhachary, MD, PhD

    Washington University in St. Louis
    St. Louis, MO, United States

    Disclosure(s): Biogen: Advisor or Review Panel Member (Ongoing), Grant/Research Support (Ongoing), Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Ongoing); Capricor: Advisor or Review Panel Member (Ongoing), Grant/Research Support (Ongoing); Edgewise: Grant/Research Support (Ongoing); Epirium: Advisor or Review Panel Member (Terminated), Grant/Research Support (Terminated); Genentech: Grant/Research Support (Ongoing); NML: Grant/Research Support (Ongoing)

Nervous system manifestations of Sjogren’s syndrome manifest in multiple forms, resulting in marked heterogeneity of clinical presentation and a complex algorithm for diagnostic evaluation. Management recommendations lack strong empiric evidence. Postural tachycardia syndrome and other forms of dysautonomia are increasingly associated with Sjogren’s Syndrome and can be challenging to diagnose and manage. Novel insights into the connection between immunity and migraines is opening horizons to deeper understanding of certain neurologic manifestations of Sjogren’s Syndrome.

Learning Objectives:

  • Delineate the presentation and evaluation of dysautonomia in Sjogren’s Syndrome
  • Describe new insights on the interplay of migraines and Sjogren’s Syndrome
  • Synthesize a management strategy for neurological complications of Sjogren’s Syndrome

Presentations:

  • 4:00 PM – 4:15 PM PT
    The Approach to Evaluating Dysautonomia in Sjögren's Disease

    Speaker: Brent Goodman, MD – Mayo Clinic

  • 4:15 PM – 4:30 PM PT
    Update on the Pathogenesis of Migraines in Sjögren's Disease

    Speaker: Arun Varadhachary, MD, PhD – Washington University in St. Louis

  • 4:30 PM – 4:45 PM PT
    Practical Management Strategies for Neurologic Complications of Sjögren's Disease

    Speaker: Julius Birnbaum, MD – 1 University of Pittsburgh Medical Center

  • 4:45 PM – 5:00 PM PT
    Q&A