Stanford
Atherton, CA, United States
Dr. Michael Longaker’s research focuses on wound repair and fibrosis, with specific applications to different systems between fetal and post-natal wound healing. His research has opened up two fields: fibroblasts heterogeneity / regeneration during wound repair and skeletal stem cells. He made the discovery that embryos heal without a scar early in gestation and transition to scarring late in gestation a while as a post-doc at UCSF. Over the past three decades he has worked out how mechanical forces promote scarring in adult animals. His laboratory identified the fibroblast lineage responsible for scarring in mouse dorsal wounds (Science, 2015). Most recently, he achieved true regeneration without scarring during adult mouse wound healing and has worked out mechanisms through which this occurs (Science, 2021; Cell Stem Cell, 2022; Cell Stem Cell 2022; Science 2023; Cell Stem Cell, 2023).
He has received numerous prestigious awards, including Medallion for Scientific Achievement and the Flance-Karl Award from the American Surgical Association, Lifetime Achievement Award, Society of University Surgeons; Dedication of Owen Wangensteen Scientific Forum, American College of Surgeons. He is a member of the American Society for Clinical Investigation, Association for American Physicians, and the National Academy of Medicine. He has published over 1400 papers and has over 100 issued and / or applied for patents.
How Fibroblasts Can Participate in Scarless Regeneration
Monday, November 13, 2023
12:30 PM – 12:45 PM PT
Disclosure(s): No financial relationships with ineligible companies to disclose